The disconnection approach
Basic principles : synthons and reagents synthesis of aromatic compounds
Strategy I : the order of events
One-group C-X disconnections
Strategy II : chemoselectivity
Two-group C-X disconnections
Strategy III : reversal of polarity, cyclisations, summary of strategy
Strategy IV : protecting groups
One group C-C disconnections I : alcohols
General strategy A : choosing a disconnection
Strategy V : stereoselectivity A
One group C-C disconnections II : carbonyl compounds
Strategy VI : regioselectivity
Strategy VII : use of acetylenes (alkines)
Two-group C-C disconnections I : Diels-Alder reactions
Strategy VIII : introduction to carbonyl condensations
Two-group C-C disconnections II : 1,3-difunctionalised compounds
Strategy IX : control in carbonyl condensations
Two-group C-C disconnections : 1,5-difunctionalised compounds
Strategy X : aliphatic nitro compounds in synthesis
Two-group disconnections IV : 1,2-difunctionalised compounds
Strategy XI : radical reactions in synthesis
Two-group disconnection V : 1,4-difunctionalised compounds
Strategy XII : reconnection
Two-group C-C disconnections VI : 1,6-diCarbonyl compounds
General strategy B : strategy of carbonyl disconnections
Strategy XIII : introduction to ring synthesis : saturated heterocycles
Strategy XIV : rearrangements in synthesis
Four-membered rings : photochemistry in synthesis
Strategy XV : the use of ketenes in synthesis
Strategy XVI : pericyclic reactions in synthesis : special methods for five-membered rings
General strategy C : strategy of ring synthesis
Strategy XVII : stereoselectivity B
General strategy D : advanced strategy.
